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In our opinion, the increase in smoking with the universal custom of inhaling is probably a responsible factor, as the inhaled smoke, constantly repeated over a long period of time, undoubtedly is a source of chronic irritation to the bronchial mucosa. Tobacco Smoking As A Possible Etiologic Factor In Bronchogenic Carcinoma (10 pages) Original article by Ernst Wynder and Evarts A

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But that was 20 years ago, when teen smoking reached its peak and before campaigns like the CDCs Tips from Former Smokers and Truth Initiative warned young people not to use tobacco

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